Prolonging lifespan of the cells could have been due to reactivation of telomerase gene in somatic cells
Copper Chelation and Delivery At the most fundamental level, GHK functions as a copper chelator and delivery system - the tripeptide binds Cu with exceptionally high affinity (binding constant approximately 10 M, among the highest known for biological copper chelators), forming a square planar coordination complex where the copper ion is coordinated by the nitrogen atoms of the terminal amino group, the two peptide bonds, and the imidazole nitrogen of histidine
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Moreover, in these sporadic cases of severe G6PD deficiency with CGD, PPP flux is markedly diminished to the point of impaired NADPH oxidase activity and absent NETosis (28), and the impaired phagocytic respiratory burst was clinically linked to cases of mycobacterial infection (29)