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Yang W, Xiao C, Zheng J, Song J, Li XG

Insulin enhances glucose uptake into skeletal muscle and adipose tissues by activating the PI3K/Akt signalling pathway, regulating GLUT4 trafficking from intracellular compartments (known as the GLUT4-storage compartment (GSC), or GLUT4-storage vesicles (GSVs)) to the plasma membrane (PM) in adipocytes, or sarcolemma and transverse tubule membrane in myocytes (Figure 1)

The death of dopamine-producing neurons in the substantia nigra causes Parkinsons disease.[ref] MPTP was discovered as a contaminant in illegal drugs that caused immediate and irreversible Parkinsons symptoms

But larger GST-fusion proteins mean fewer can bind to each bead at the same time without running into one another (Figure 4)