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This argument is plausible it reflects a well-documented problem in drug development where unpatentable compounds struggle to attract industry funding regardless of their scientific merit but it should be noted that this explanation, while widely discussed, has not been formally established in the published literature as the primary reason for the evidence gap

Lorom, M

[DOI] [PMC free article] [PubMed] [Google Scholar] 109.Klein E.A., Thompson I.M., Jr., Tangen C.M., Crowley J.J., Lucia M.S., Goodman P.J., et al

The non-radical species such as hydrogen peroxide, hypochlorous acid, hypobromous acid and other species, can induce cellular damage after being converted into more aggressive radical species [13, 14]