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It is likely, although not established, that transport across the blood-brain barrier is the more important of these two mechanisms

This allows NRF2 to bind to the ARE and induce the expression of protective antioxidant genes [218]

In cancer treatment, bioinformatics helps researchers to accurately identify potential drug targets and prognostic biomarkers by integrating multi-omics data, deeply analyzing and validating the mechanisms of action of drugs and predicting drug resistance, which can significantly improve the precision and effectiveness of treatments (Rehman et al., 2020

Phacoemulsification is the gold standard for cataract surgery in the developed world, whereas manual small incision cataract surgery is used frequently in developing countries