Eli Lilly sponsored SURMOUNT-5, (NCT05822830), a Phase IIIb, open label, multi-centre, randomised clinical trial to compare the efficacy and safety of tirzepatide (Zepbound) versus semaglutide (Wegovy) in overweight or obese adults and at least one additional named weight-related comorbidity that was not T2D 24
Glutathione reduces oxidative stress, which may help create a healthier internal environment for weight management
Thus we propose that along with clinical examination, estimation of oxidative stress may serve as supportive additional biochemical markers for early diagnosis and therapeutic intervention
Bailey SJ, Blackwell JR, Williams E, Vanhatalo A, Wylie LJ, Winyard PG, Jones AM