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To examine the capacity of WT and Mda5 -/- HSCs to repopulate lethally irradiated recipients, we sorted and transplanted 100 LSK-SLAM HSCs from young or aged WT or Mda5 -/- mice together with aged-matched CD45.1 competitors into CD45.1 lethally irradiated recipients, followed by whole bone marrow competitive secondary transplantations

Pyrimidine analogs 38, and 39 Ginsenosides are a class of bioactive compounds found in the roots, stems, and leaves of plants in the genus Panax, particularly Panax ginseng (Asian ginseng) and Panax quinquefolius (American ginseng)