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Research suggests it acts through modulation of several interconnected signaling pathways simultaneously a broad mechanism of action that helps explain its observed multisystemic effects in laboratory models, and that also makes it challenging to evaluate through conventional single-target drug development frameworks

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During first 12h epoch, no significant BP difference was observed, while during second 12h epoch, systolic BP (SBP) was significantly higher in MBE group (GEE P = 0.027)