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From the present review, it is evident that small peptides exert towards oral cells and tissues an antitumor activity through apoptosis or selective necrosis of cell lines specifically associated with oral squamous cell carcinoma, an antimicrobial function by maintaining the balance of the oral microbiome, an immunomodulatory function through up and down-regulation of important genes involved in immunoregulatory gene cascades, and finally a cell differentiation function towards major stem cells in the oral cavity, even in absence of growth factors [21, 27,28,29,30,31, 34, 35]

One example of an auris-acceptable solvent release gel formulation is the SABER Delivery System marketed by DURECT Corporation

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Scar Appearance Some users find that GHK-Cu helps improve the appearance of scars over time by supporting proper tissue remodeling