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ALA is a clinically established, pathogenesis-oriented option for managing neuropathy, working to support endoneural blood flow, reduce advanced glycation end-products (AGEs), and promote the regeneration of damaged nerve fibers

94 Peptide YY The endocrine L cells of the large and small bowel produce Peptide YY 3-36 (PYY 3-36 ) in response to the presence of food

However, theoretical concerns remain about long-term effects on glucose homeostasis with chronic use, particularly in individuals predisposed to diabetes

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