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3 After roughly 18 months, participants lost about 10 percent of body weight, and average total testosterone increased by 18 percent, suggesting that weight reduction from GLP-1 therapy may help reverse obesity-related low testosterone

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[DOI] [PMC free article] [PubMed] [Google Scholar] 31.Matthews M., Nigg J.T., Fair D.A

It should be noted that men with known conditions that would cause inflammation (such as genital tract infections, varicocele) or that used alcohol, smoked, or were currently taking antioxidants were all excluded from the study to create a more consistent base-line of existing oxidative stress (inflammation) between the groups This study also showed that the higher the measured levels of ROS, the more damage there was to sperm function