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In addition, Scrophulariae Radix inhibits abnormal thyroid cell proliferation by activating the MST1/Hippo pathway while promoting apoptosis and autophagy (100, 101)

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Ferroptosis inhibition in long-lived plasma cells might provide a strategy to prolong antibody responses in vaccination or autoimmune diseases where excessive autoantibody production is a concern (45, 50, 7478)

One expert noted that TB-500 was found to accelerate tumor growth in animal experiments, that other growth-related peptides might carry the same risk, and that other peptides could cause hormonal imbalances