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Allergic sensitization to copper compounds has been reported anecdotally but is not well-characterized in controlled GHK-Cu trials

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The pharmacokinetic and tissue-distribution profile of the compound has been characterized at varying levels of detail across the different research contexts

This severe localized depletion allows neuroinflammation to run rampant, directly causing the severe cognitive impairment, memory loss, and neurological symptoms commonly referred to as "brain fog." Historically, medical science viewed the role of glutathione in chronic illness as a simple equation of "depletion." However, cutting-edge research has revealed a much more dynamic and complex reality