Enhancing GSH, mainly through NAC, GSH precursors rich in cysteine (whey protein, whey protein isolate rich in cysteine) or pro-GSH compound administration, becomes a potential treatment option for inflammatory diseases by reducing oxidative stress and cytokine expression especially in diabetic patients that also are at risk of more severe COVID-19 disease (299)
[Google Scholar] [PubMed] Lee E, Ryan S, Birmingham B, Zalikowski J, March R, Ambrose H, Moore R, Lee C, Chen Y, Schneck D (2005)
Resolution of the curcumin antioxidant controversy
Although glutamine is a major gluconeogenic substrate, mainly in the kidney, alanine also contributes donating carbon for gluconeogenesis, being essentially confined to the liver [147]