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The peptide also demonstrates significant effects on dendritic spine formation and synaptic density, contributing to enhanced cognitive function

The combined anti-inflammatory and antioxidant effects converge to achieve chondroprotection (Figure 2)

Basatvat S, Russell JM, Saare M, Thurston LM, Salumets A, Fazeli A (2021) Potential innate immunity-related markers of endometrial receptivity and recurrent implantation failure (RIF)

Upon tissue disruption, danger-associated molecular patterns (DAMPs) Such as extracellular ATP, high-mobility group box 1 (HMGB1), and uric acid crystals are released from damaged cells [26, 27], while PAMPs from the wound microbiome including lipopolysaccharide (LPS) from Gram-negative bacteria, lipoteichoic acid from Gram-positive bacteria, and bacterial DNA-are detected by pattern recognition receptors (PRRs) such as NLRP3, AIM2, or NLRC4 [28]