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Loss of RPRM expression is associated with increased proliferation and growth of GC cells, and this poorly understood gene family has the potential for new translational applications as biomarkers for early screening in the future ( 3.1.4 Pancreatic cancer (PC) Pancreatic cancer is a highly aggressive malignancy that is often not detected until it has reached an advanced stage

In patients with alcohol dependence and delirium unresponsive to high doses of benzodiazepines, alcoholic pellagra should be considered, since chronic alcoholism leads to a lack of tryptophan 2,3-dioxygenase, an enzyme linked to niacin synthesis

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