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In this cycle, vitamin B 12 is a necessary cofactor for methionine synthase, an enzyme involved in the methylation of homocysteine to methionine

Supports Red Blood Cell Production and Prevents Anemia Vitamin B12 is critical for the production of red blood cells, which carry oxygen to the bodys tissues and organs

Secondary objectives Measure whether daily maternal administration of 50 g vitamin B 12 from early pregnancy until 6 months postpartum improves haemoglobin concentration of the mother and infant, and also assess the relationship between maternal and infant haemoglobin concentration on cognitive outcomes at 6 and 12 months of age

ETD, estimated treatment difference