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The efflux transporters transport a wide range of lipophilic molecules, whereas nutrient transporters ensure the supply of specific nutrients across the BBB and help in the removal of waste products by their transport from CNS into the blood [6, 24]

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Effective pharmacological therapies include statins for the treatment of dyslipidemia, antiplatelet medicines for the reduction of prothrombotic risk, and insulin sensitizers for the prevention of diabetes

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