& Abdul-Ghani, M
The synthesis process carefully manages the incorporation of alpha-aminoisobutyric acid (Aib) at the N-terminus and the D-amino acids (D-2-naphthylalanine and D-phenylalanine), which do not occur in natural proteins but are critical to the peptides final properties
The problem is that the digestive process, particularly stomach acid and the enzyme gamma-glutamyltransferase present in the gut lumen, can cleave glutathione into its constituent amino acids (glutamate, cysteine, glycine) before it is absorbed intact
The study was presented as an abstract at the Experimental Biology international conference, in San Diego, on April, 4 th , 2016: Zavorsky G.S, Ueberschlag S.L., Seay J.R, Roberts A.H., DeSpirito P.C., Stith J.M., Folz R.J., Carter K.A., Weiss, E.P