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Jeschke, V., Gershenzon, J

However, regular use over several days or weeks may be necessary for therapeutic advantages such tissue healing or inflammation reduction

And as it does, a picture is emerging that looks very familiar to practitioners of functional and integrative medicineone defined by viral persistence, mitochondrial dysfunction, chronic inflammation, immune dysregulation, microbiome disruption, and autonomic nervous system damage

In autoimmune diseases such as systemic lupus erythematosus (SLE), mitochondrial damage and the release of mitochondrial DNA (mtDNA) into the cytoplasm and extracellular space have been observed [130]