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In fact, a majority of our patients respond well to their initial therapeutic plan but some may need adjustments along their journey to success

doi:10.1016/j.jaci.2020.01.017

In this phase II of the test, the home arm, the arm explored in phase I, designated the familiar arm, and the third arm previously closed arm, designated the novel arm, were open for exploration

In two of the OPM-2 xenografts, BSO+L-PAM reduced tumor volumes of 1330 mm 3 and 972 mm 3 to 2), inducing CRs in majority of the mice treated (21/25), achieving MCRs in 6/25 mice, and doubling the median EFS relative to L-PAM alone ( P 80% was not cytotoxic, whereas three cell lines were affected by BSO