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In some embodiments, the lipid-based drug delivery formulation or composition comprises about 25% v/v or less of any one or more chemical penetration enhancer(s), most preferably from about 2% to 15% v/v, although the exact formulation or composition will vary depending on the presence and amounts of excipients, preservatives, water, pH modulators, and the like included therein

More than half a decrease in mitochondrial I activity has been observed in patients with sporadic PD and parkin mutations

[DOI] [PubMed] [Google Scholar] 53.Baraldo S, Faffe DS, Moore PE, Whitehead T, McKenna M, Silverman ES, et al

R.et al (1999)