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If low levels of B 12 remain for a long time, the condition also can lead to irreversible damage to nerve cells, which can cause the following symptoms: numbness and tingling in the hands and feet difficulty walking muscle weakness irritability memory loss dementia depression psychosis

Beyond behavioral assessments, the study also delved into neurobiological changes through oxytocin receptor autoradiography

Therefore, a comprehensive synthesis of available evidence is needed to clarify whether non-invasive routes provide efficacy comparable to intramuscular therapy