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An integrated metabolomics workflow for the quantification of sulfur pathway intermediates employing thiol protection with N-ethyl maleimide and hydrophilic interaction liquid chromatography tandem mass spectrometry

The ASCO guidelines identify duloxetine as the sole recommended treatment for CIPN, particularly in cases associated with oxaliplatin and paclitaxel, due to its proven efficacy in alleviating neuropathic symptoms (Loprinzi et al., 2020

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