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At this time it is unclear whether free radical involvement in Parkinson's disease is a primary or secondary event in nigral cell death or whether it occurs early or late in the disease process

This mismatch between lifestyle and biology drives issues like: Blood sugar spikes and crashes from processed carbs Weight gain and stubborn fat driven by insulin resistance Sluggish metabolism from sedentary routines Chronic inflammation fueled by stress and poor diet Digestive imbalances from over-reliance on antibiotics and low-fiber diets Berberine uses sit right at the intersection of these problems

Alzheimer's Disease: A Matter of BloodBrain Barrier Dysfunction? Journal of Experimental Medicine 214: 31513169

& Douglas, R