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Probably, the consumption of GSH and other antioxidants in reactions of degradation of lipid peroxidation products, affects the decrease of GPx and GST enzymes activity, and as the process of cataractogenesis progresses towards mature cataract, all lens structures become affected by the changes, which probably leads to the change of enzyme molecules themselves

Another example involves folic acid during pregnancy

FIGURE 7 3.7 GHK-Cu suppresses inflammatory cytokines partly via STAT3 inhibition We also explored the role of STAT3 in modulating inflammatory factor expression by GHK-Cu in LPS-stimulated MPMs transfected with siSTAT3

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