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The accumulation of amyloid- (A) is a pathological hallmark of AD, with A being produced through the cleavage of amyloid precursor protein (APP) by -and -secretases, generating peptides of A of varying length (Murphy and LeVine, 2010)

J Diabetes Complicat 18:7985 Hahn K, Robinson B, Anderson C, Li W, Pardo CA, Morgello S, Simpson D, Nath A (2008) DIfferential effects of HIV infected macrophages on dorsal root ganglia neurons and axons

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Liao, Y., Smyth, G