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A wide spectrum of dendrimer architectures have been developed through selective surface functionalization using groups such as OH, SH, NH, COOH, azido, and allyl moieties, as well as through conjugation with carbohydrates, peptides, ligands, or other targeting motifs

However, when PDA@Pt is combined with laser therapy (808 nm, 1 W/cm 2 ), the red fluorescence nearly disappeared

doi: 10.3389/fonc.2018.00411 20 ReisLMDAdamoskiDOrnitz Oliveira SouzaRRodrigues AscenoCFSousa de OliveiraKRCorra-da-SilvaFet al

Conditions such as Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), Fibromyalgia (FM), and Gulf War Syndrome (GWS) are examples of these chronic illnesses that are triggered by different factors but share overlapping clinical symptoms, in particular profound fatigue (see Figure 1)