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It is of great theoretical significance and practical value to clarify the mechanism of ferroptosis and its role in various diseases, and to develop corresponding inhibitory drugs according to different stages and targets of ferroptosis

The use of Drosophila bring to the study of oxidative liver injury many advantages, including ease of genetic manipulation, availability of genetic mutants and constructs, ease of germ-free generation, relatively short lifespan, amenability to high-throughput screening, and overall cost relative to murine models 40

doi: 10.3390/molecules27082546 [DOI] [PMC free article] [PubMed] [Google Scholar] 48.Gopal S, Borovok I, Ofer A, et al

By sixth year, REM sleep time stabilizes to about twenty five percent of the total sleep