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J Investig Allergol Clin Immunol 27(3):175182

We have previously demonstrated that enhanced oxidative phosphorylation and reduced dependence on glycolysis is associated with a radioresistant phenotype in oesophageal adenocarcinoma (21, 22) and rectal adenocarcinoma (23), respectively, suggesting that targeting energy metabolism, specifically oxidative phosphorylation, may be an effective strategy to enhance therapeutic response to neoCRT (42)