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[DOI] [PMC free article] [PubMed] [Google Scholar] 78.Lee J., Roh J.L

Results In vitro ROS assay The antioxidant activity of NAC and NACET was assessed in an in vitro ROS assay in ARPE-19 cells using TBHP (200 M) as the oxidative stress-generating reagent

It also enhances glucose and lipid metabolism by upregulating protective proteins such as glutathione peroxidase 4 (GPX4) and ferritin heavy chain 1, while downregulating ferroptosis-related mediators including ACSL4 and transferrin receptor 1 (213)

Similarly, a systematic review that examined alternatives to antacid medications concluded that alkaline reduced water may be effective when combined with a low acid diet for the management of laryngopharyngeal reflux (4549)