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Key points Blood pressure is determined by the interplay of genetic factors including rare variants with large effect sizes that cause monogenic hypertension syndromes and common variants with small effect sizes that contribute to polygenic cases of hypertension and non-genetic factors such as diet and the microbiome

Originally derived from human gastric juice, this powerful 15-amino-acid peptide has moved well beyond the fitness universe, stirring up serious interest in both the medical and biohacking worlds

Most people will see an improvement. Ruscio recommends a three-tier approach: a Lactobacillus and Bifidobacterium blend, the probiotic yeast Saccharomyces boulardii (for more information, see Protective Yeasts at below), and a soil-based probiotic

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