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Rather, MTs were shown to have a novel function in protecting the heart by mitigating myocardial infarction-induced cardiomyocyte apoptosis through the activation of the mTORC2/FoxO3a/Bim pathway rather than merely through their ROS sequestering ability

GFAP: glial fibrillary acidic protein

Indeed, the translocator protein (Tspo), a protein that binds to the voltage-dependent anion channel (VDAC) and interferes with redox balance 69,70,71 was upregulated after sUA+LPS stimulus in all macrophages analyzed, but in a more pronounced way in WT and Myd88 / cells

doi: 10.1038/ncb1450 124 PoggiMKaraIBrunelJMLandrierJFGoversRBonardoBet al