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Therefore, early diagnosis by cystoscopy is justified in patients suspected to have Hunner lesions, without requiring them to fail other behavioral or medical treatments before recommending cystoscopy

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During endothelial dysfunction, structural and functional abnormalities arise in the endothelial cells, impairing their ability to regulate vasodilation, thrombosis, and vascular wall repair

I have heard that B12 have improved people's fertility, so maybe heavy periods is what should be normal for you