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C/EBP confers dependence to fatty acid anabolic pathways and vulnerability to lipid oxidative Stress-Induced ferroptosis in FLT3-Mutant leukemia

It plays a pivotal role in glucose metabolism and appetite regulation through multiple mechanisms: Enhances insulin secretion: GLP-1 stimulates pancreatic -cells to release insulin in a glucose-dependent manner Suppresses glucagon: Reduces hepatic glucose production Delays gastric emptying: Creates prolonged satiety Central nervous system effects: Acts on appetite centers in the brain to reduce hunger and food intake Protects pancreatic -cells: Promotes cell proliferation and inhibits apoptosis GLP-1 Receptor Agonists in Clinical Practice GLP-1 receptor agonists (GLP-1 RAs) are medications designed to mimic the action of endogenous GLP-1 but with enhanced pharmacokinetic properties

And had reduced cognitive decline and less depression and anxiety

Both BMAC and MFAT deliver similar results, although BMAC is generally used for younger, bone-involved OA, while MFAT is considered a better fit for elderly patients and those with higher body weight