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Treatment with silibinin elevated the phosphorylation of Akt, increased the expression of Wnt5a and Lef1, and promoted the TCF/Lef reporter activity

These compounds have been shown to protect against oxidative damage and support eye health

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Although lactate has long been considered a by-product of anaerobic metabolism, recent evidence showed that it can be found within the extracellular space of human neuronal tissue under aerobic conditions 19 , suggesting that it could have a physiological role in the brain as a supplemental energy source or even as a signalling molecule 20