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What makes this particularly relevant is how common sleep disruption is and how rarely it gets factored into gut health investigations

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GDH3 is a glucose-repressed gene and consequently the presence of Gdh3 protein in the pool was very low [15, 21,22,23]

However, robust quantitative translation between administered experimental doses and plausible human internal burdens remains highly uncertain due to variability in exposure assessment assumptions, limited size-resolved data on internal PET burdens in humans (particularly for the nanoscale fraction), and methodological constraints in detecting and characterising sub-micrometre particles in complex biological matrices