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"Vitamin B12 deficiency among adult diabetic patients in Uganda: relation to glycaemic control and haemoglobin concentration"

There is an association with "watermelon stomach" (GAVE) and pernicious anemia

You may want to talk with a doctor about B12 shots if you regularly experience: Persistent fatigue and lethargy Muscle aches and joint pain Loss of appetite Nausea, constipation, diarrhea, or cramping Poor memory or difficulty concentrating Mood swings Can B12 Injections Help With Mood Enhancement and Mental Clarity

[10] Vitamin B is an essential nutrient for fetal development, and untreated B deficiency in a pregnant woman can lead to serious neurological damage in the infant