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Epidemiological studies consistently demonstrate that elevated circulating BCAA levels are closely associated with increased risk of insulin resistance (IR) and type 2 diabetes mellitus (T2DM) (132, 133)

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For now, experts use semen analysis and DNA fragmentation index along with lifestyle analysis, exposure history, and health history to assess whether oxidative stress affects a mans fertility

Maccarrone and Ullrich suggested that the consideration of the redox state may be more reflective of the physiologically and pathological effects of oxidative stress than the mere absolute amounts of antioxidants and oxidants