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For cells treated with the AM form of RT, real-time ratiometric images of the rapid changes of intracellular GSH concentrations in single cells can be generated by dividing the fluorescence intensity values for the 405 nm channel by the 488 nm channel at each corresponding pixel (Fig

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The Y- and radial arm mazes were used to assess and score spatial working memory as previously described[54,55]

With increasing research activity, several metabolic pathways related to ferroptosis have been reported, including the tetrahydrobiopterin (BH 4 )/coenzyme Q10 (CoQ 10 ) system and the dihydroorotate dehydrogenase (DHODH)/CoQ 10 axis [20]