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Due to the continuous activation of the ERK-1/2 pathway in glial cells, after GSH depletion, the neurotrophic properties do not turn into neurotoxicity, which aggravates PD pathology ( Fibronectin is a macromolecular glycoprotein that widely exists in the extracellular matrix and regulates the synaptic transmission of DA neurotransmitters

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However, for individuals who require high doses or have difficulty absorbing the vitamin, injections may be a more practical option

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