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Proposed mechanisms include upregulation of growth-hormone-receptor expression in injured tissue, VEGF-driven angiogenesis, modulation of the nitric-oxide pathway in vascular endothelium, and activation of FAK-paxillin signaling

Larger randomised trials are needed before definitive clinical recommendations can be made.

The general dosage for horses is 3 sprays daily

Regular use of copper peptides delivers visible improvements such as: Smoother texture and fewer fine lines Improved firmness and elasticity Reduced redness and more balanced tone Enhanced hydration and resilient barrier Most users notice a soft glow within 48 weeks, with deeper collagen and elastin improvements by 12 weeks