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Activation and proteasomal degradation of Rho GTPases by cytotoxic necrotizing factor-1 elicit a controlled inflammatory response

The most commonly reported side effects for both agents are gastrointestinal, including nausea, vomiting, diarrhoea, and constipation, particularly during dose escalation

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Pluvicto is the brand name for the radiopharmaceutical, which includes lutetium-177 (Lu-177), a radioisotope only produced in the United States at the University of Missouri Research Reactor (MURR)