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Two antisense oligonucleotides that specifically interact with the mRNAs of the protein kinase C-, responsible for tyrosinase phosphorylation and thus its activation [115], decreased tyrosinase activity in cultured melanocytes and reduced hand pigmentation in volunteers after applying a care product containing these synthetic agents [116]

Introduction Despite considerable technological developments and continuous research to find and implement an effective and safe drug, there are still none that have positive therapeutic effects, target multiple disease entities, and, at the same time, have no side effects

They collected peripheral blood samples from PCOS patients