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doi: 10.1016/j.tifs.2019.11.022 90

It took years to uncover their existence, let alone to analyze their efficacy or sanction the athletes who used them

Although GSSG represents approximately 1% of the total glutathione in the cell under basal conditions, a striking increase is found in cells undergoing oxidative stress

In fact, the use of GSTP1 knockout mice demonstrated that loss of GSTP1 expression increases sensitivity to metabolic or environmental toxins and promotes mutations and cancer development (Coughlin and Hall, 2002a,b)