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Description

Chonnam Med

The accumulation of DPP9 leads to the overactivation of NRF2 and its transcriptional target SLC7A11, which inhibits ferroptosis and induces the resistance of ccRCC cells to sorafenib (142)

We suspect the large size 64 and complex protein folding with -helical structures at the surface of RuBisCO contribute to the ordering of water molecules and efficient ice nucleation

Notably, adding a mGluR2/3 antagonist was suggested to inhibit the action of spadin, pointing towards a dependency of spadin on mPFC TREK-1 channels that are possibly linked to mGluR2/3 receptors