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Together, these data show that FOXO4-DRI potently and selectively reduces the viability of senescent cells by competing with FOXO4-p53 binding, thereby triggering release of active p53 to the cytosol and inducing cell-intrinsic apoptosis through Caspase-3/7

103 Pineda-MolinaE.KlattP.VazquezJ.MarinaA.Garcia De LacobaM.Perez-SalaD.et al (2001)

Improved energy levels: Reduction in afternoon fatigue and improved stamina during exercise, particularly in patients who were already physically active before starting

Removal of AMPA receptors (AMPARs) from synapses is preceded by transient endocytosis of extrasynaptic AMPARs