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DNA Stability Investigations propose that GHK may support the activity of DNA repair-related genes, potentially linked to mitigating age-associated decline

Additionally, a study by Liu et al (41) demonstrated that miR-196a promotes the development of non-small cell lung cancer by downregulating the expression of GPX3 and activating the JNK pathway, thereby enhancing the proliferation, differentiation, self-renewal ability and invasiveness of cancer stem cells (CSCs) (41)

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Luan et al found endothelial dysfunction in hypertension-associated ED rats, with the increased expression of the NOD-like receptor thermal protein domain associated protein 3 inflammasome, caspase-1, gasdermin-D, and the pro-inflammatory cytokines interleukin-1 and interleukin-18 in the CC, supporting the involvement of pyroptosis in vascular endothelial injury related to hypertension-associated ED [119]