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Following recommendations from previous literature [33], we used p -values from the models with M-value to assess the statistical significance and reported effect size estimates from the models with beta-value for better interpretations

The test tubes were placed in boiling water bath (100 C) for 2 h

Clinics offering them purely for cosmetic lightening should be approached with caution and discussed thoroughly with a qualified doctor

Use of a semisynthetic Nrf2 inducer (dimethyl fumarate) has demonstrated efficacy and reduced systemic inflammation in an obstructive sleep apnea clinical study [275], which suggests that there may be a similar role for SF