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This study demonstrated that cultured hepatocytes treated either with a precursor of GSH, such as L-cysteine or N-acetylcysteine, or with its soluble ethyl ester form, boosts the levels of cellular GSH, which upregulates CYP27A1, CYP27B1, and VDR but downregulates CYP24A1

The glutathione-deficient, cadmium-sensitive mutant, cad2-1, of Arabidopsis thaliana is deficient in gamma-glutamylcysteine synthetase

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