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Funding This work was supported by National Natural Science Foundation of China grants (82200509, 82160094 to MXJ), Natural Science Foundation of Jiangxi Province (20252BAC240143 to MXJ), Jiangxi province Science and Technology Program of the Health Commission (202311127 to MXJ), and the Jiangxi Province Key Laboratory of bioengineering drugs (2024SSY07061)

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